Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Mbp  myelin basic protein   (Synonyms: golli-mbp, Hmbpr, jve)
Results	Reference
1	J:226852 Baroti T, Zimmermann Y, Schillinger A, Liu L, Lommes P, Wegner M, Stolt CC, Transcription factors Sox5 and Sox6 exert direct and indirect influences on oligodendroglial migration in spinal cord and forebrain. Glia. 2016 Jan;64(1):122-38
1	J:95822 Cai J, Qi Y, Hu X, Tan M, Liu Z, Zhang J, Li Q, Sander M, Qiu M, Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling. Neuron. 2005 Jan 6;45(1):41-53
1	J:69975 Cai J, Qi Y, Wu R, Modderman G, Fu H, Liu R, Qiu M, Mice lacking the Nkx6.2 (Gtx) homeodomain transcription factor develop and reproduce normally. Mol Cell Biol. 2001 Jul;21(13):4399-403
1	J:160023 Cossais F, Sock E, Hornig J, Schreiner S, Kellerer S, Bosl MR, Russell S, Wegner M, Replacement of mouse Sox10 by the Drosophila ortholog Sox100B provides evidence for co-option of SoxE proteins into vertebrate-specific gene-regulatory networks through altered expression. Dev Biol. 2010 May 1;341(1):267-81
1	J:212081 Dai ZM, Sun S, Wang C, Huang H, Hu X, Zhang Z, Lu QR, Qiu M, Stage-specific regulation of oligodendrocyte development by Wnt/beta-catenin signaling. J Neurosci. 2014 Jun 18;34(25):8467-73
1	J:289244 Elsesser O, Frob F, Kuspert M, Tamm ER, Fujii T, Fukunaga R, Wegner M, Chromatin remodeler Ep400 ensures oligodendrocyte survival and is required for myelination in the vertebrate central nervous system. Nucleic Acids Res. 2019 Jul 9;47(12):6208-6224
1	J:162692 Finzsch M, Schreiner S, Kichko T, Reeh P, Tamm ER, Bosl MR, Meijer D, Wegner M, Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage. J Cell Biol. 2010 May 17;189(4):701-12
1	J:130977 Finzsch M, Stolt CC, Lommes P, Wegner M, Sox9 and Sox10 influence survival and migration of oligodendrocyte precursors in the spinal cord by regulating PDGF receptor {alpha} expression. Development. 2008 Feb;135(4):637-46
1	J:155627 Genethliou N, Panayiotou E, Panayi H, Orford M, Mean R, Lapathitis G, Gill H, Raoof S, De Gasperi R, Elder G, Kessaris N, Richardson WD, Malas S, SOX1 links the function of neural patterning and Notch signalling in the ventral spinal cord during the neuron-glial fate switch. Biochem Biophys Res Commun. 2009 Dec 25;390(4):1114-20
1	J:206315 Hoffmann SA, Hos D, Kuspert M, Lang RA, Lovell-Badge R, Wegner M, Reiprich S, Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes. Development. 2014 Jan;141(1):39-50
1	J:153666 Kawase-Koga Y, Otaegi G, Sun T, Different timings of Dicer deletion affect neurogenesis and gliogenesis in the developing mouse central nervous system. Dev Dyn. 2009 Nov;238(11):2800-12
1	J:221126 Lee HK, Chaboub LS, Zhu W, Zollinger D, Rasband MN, Fancy SP, Deneen B, Daam2-PIP5K is a regulatory pathway for Wnt signaling and therapeutic target for remyelination in the CNS. Neuron. 2015 Mar 18;85(6):1227-43
1	J:338173 Liu Z, Hu X, Cai J, Liu B, Peng X, Wegner M, Qiu M, Induction of oligodendrocyte differentiation by Olig2 and Sox10: evidence for reciprocal interactions and dosage-dependent mechanisms. Dev Biol. 2007 Feb 15;302(2):683-93
1*	J:75868 Lu QR, Sun T, Zhu Z, Ma N, Garcia M, Stiles CD, Rowitch DH, Common developmental requirement for olig function indicates a motor neuron/oligodendrocyte connection. Cell. 2002 Apr 5;109(1):75-86
1*	J:236148 Muth KN, Piefke S, Weider M, Sock E, Hermans-Borgmeyer I, Wegner M, Kuspert M, The Dual-specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes. Glia. 2016 Dec;64(12):2120-2132
1	J:210099 Paes de Faria J, Kessaris N, Andrew P, Richardson WD, Li H, New Olig1 null mice confirm a non-essential role for Olig1 in oligodendrocyte development. BMC Neurosci. 2014;15:12
1	J:132162 Petryniak MA, Potter GB, Rowitch DH, Rubenstein JL, Dlx1 and Dlx2 control neuronal versus oligodendroglial cell fate acquisition in the developing forebrain. Neuron. 2007 Aug 2;55(3):417-33
1	J:123645 Potzner MR, Griffel C, Lutjen-Drecoll E, Bosl MR, Wegner M, Sock E, Prolonged Sox4 expression in oligodendrocytes interferes with normal myelination in the central nervous system. Mol Cell Biol. 2007 Aug;27(15):5316-26
1	J:97013 Qi Y, Cai J, Wu Y, Wu R, Lee J, Fu H, Rao M, Sussel L, Rubenstein J, Qiu M, Control of oligodendrocyte differentiation by the Nkx2.2 homeodomain transcription factor. Development. 2001 Jul;128(14):2723-33
1*	J:84432 Qi Y, Tan M, Hui CC, Qiu M, Gli2 is required for normal Shh signaling and oligodendrocyte development in the spinal cord. Mol Cell Neurosci. 2003 Jul;23(3):440-50
1	J:124679 Schreiner S, Cossais F, Fischer K, Scholz S, Bosl MR, Holtmann B, Sendtner M, Wegner M, Hypomorphic Sox10 alleles reveal novel protein functions and unravel developmental differences in glial lineages. Development. 2007 Sep;134(18):3271-81
1	J:98431 Stolt CC, Lommes P, Friedrich RP, Wegner M, Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy. Development. 2004 May;131(10):2349-58
1	J:74258 Stolt CC, Rehberg S, Ader M, Lommes P, Riethmacher D, Schachner M, Bartsch U, Wegner M, Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10. Genes Dev. 2002 Jan 15;16(2):165-70
1	J:116148 Stolt CC, Schlierf A, Lommes P, Hillgartner S, Werner T, Kosian T, Sock E, Kessaris N, Richardson WD, Lefebvre V, Wegner M, SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell. 2006 Nov;11(5):697-709
1	J:105340 Tan M, Hu X, Qi Y, Park J, Cai J, Qiu M, Gli3 mutation rescues the generation, but not the differentiation, of oligodendrocytes in Shh mutants. Brain Res. 2006 Jan 5;1067(1):158-63
1*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:260791 Truch K, Arter J, Turnescu T, Weider M, Hartwig AC, Tamm ER, Sock E, Wegner M, Analysis of the human SOX10 mutation Q377X in mice and its implications for genotype-phenotype correlation in SOX10-related human disease. Hum Mol Genet. 2018 Mar 15;27(6):1078-1092
1	J:196667 Vogl MR, Reiprich S, Kuspert M, Kosian T, Schrewe H, Nave KA, Wegner M, Sox10 cooperates with the mediator subunit 12 during terminal differentiation of myelinating glia. J Neurosci. 2013 Apr 10;33(15):6679-90
1*	J:112231 Wang SZ, Dulin J, Wu H, Hurlock E, Lee SE, Jansson K, Lu QR, An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation. Development. 2006 Sep;133(17):3389-98
1	J:306250 Wang W, Cho H, Kim D, Park Y, Moon JH, Lim SJ, Yoon SM, McCane M, Aicher SA, Kim S, Emery B, Lee JW, Lee S, Park Y, Lee SK, PRC2 Acts as a Critical Timer That Drives Oligodendrocyte Fate over Astrocyte Identity by Repressing the Notch Pathway. Cell Rep. 2020 Sep 15;32(11):108147
1*	J:288669 Wedel M, Frob F, Elsesser O, Wittmann MT, Lie DC, Reis A, Wegner M, Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation. Nucleic Acids Res. 2020 May 21;48(9):4839-4857
1	J:260476 Weider M, Starost LJ, Groll K, Kuspert M, Sock E, Wedel M, Frob F, Schmitt C, Baroti T, Hartwig AC, Hillgartner S, Piefke S, Fadler T, Ehrlich M, Ehlert C, Stehling M, Albrecht S, Jabali A, Scholer HR, Winkler J, Kuhlmann T, Wegner M, Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning. Nat Commun. 2018 Mar 2;9(1):899
1	J:224004 Weider M, Wegener A, Schmitt C, Kuspert M, Hillgartner S, Bosl MR, Hermans-Borgmeyer I, Nait-Oumesmar B, Wegner M, Elevated in vivo levels of a single transcription factor directly convert satellite glia into oligodendrocyte-like cells. PLoS Genet. 2015 Feb;11(2):e1005008
1	J:208340 Zhu Q, Zhao X, Zheng K, Li H, Huang H, Zhang Z, Mastracci T, Wegner M, Chen Y, Sussel L, Qiu M, Genetic evidence that Nkx2.2 and Pdgfra are major determinants of the timing of oligodendrocyte differentiation in the developing CNS. Development. 2014 Feb;141(3):548-55